Characterization of purinergic receptor expression in ARPKD cystic epithelia
                    
                        
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                    چکیده
منابع مشابه
Ultrasonography Lesson Renal cystic disease (ADPKD and ARPKD)
Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent hereditary renal disease and is often encountered in the work-up of renal patients. The diagnosis is obvious in advanced stages, but may be very difficult in young individuals in whom the need to provide a correct diagnosis is particularly pressing. By ultrasonography cysts are round or oval, echolucent, thin-walled, clea...
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P2X purinergic receptor (P2XR) channels bind ATP and mediate Ca(2+) influx--2 signals that stimulate secretory Cl(-) transport across epithelia. We tested the hypotheses that P2XR channels are expressed by epithelia and that P2XRs transduce extracellular ATP signals into stimulation of Cl(-) transport across epithelia. Electrophysiological data and mRNA analysis of human and mouse pulmonary epi...
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.....................................................................................................3 Acknowledgements ...................................................................................4 Publications arising from this thesis .......................................................5 Prologue ...........................................................................................
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ژورنال
عنوان ژورنال: Purinergic Signalling
سال: 2018
ISSN: 1573-9538,1573-9546
DOI: 10.1007/s11302-018-9632-5